Penn Biologists Find that Evolution is Unpredictable and Irreversible

In a paper published in the Proceedings of the National Academy of Sciences, University of Pennsylvania researchers show that evolution is both unpredictable and irreversible. Using simulations of an evolving protein, the researchers found that genetic mutations accepted via the process of evolution are usually dependent on prior mutations, and that once the mutations are accepted they become increasingly difficult to reverse. The team was comprised of postdoctoral researchers Premal Shah and David M. McCandlish in the Department of Biology, and Professor of Biology Joshua B. Plotkin.

Read the full story here.

Arts & Sciences News

Hanming Fang Named Inaugural Norman C. Grosman Professor of Economics

An applied microeconomist who integrates rigorous modeling with data analysis, Fang’s research within the field of public economics focuses on health insurance and healthcare markets.

View Article >
Julie Nelson Davis Named Paul F. Miller, Jr. and E. Warren Shafer Miller Professor of History of Art

Davis specializes in the arts and material cultures of 18th- and 19th-century Japan, with a focus on prints, paintings, and illustrated books.

View Article >
Justin Khoury Named Edmund J. and Louise W. Kahn Term Professor of Physics and Astronomy

Khoury’s research interests lie at the intersection of particle physics and cosmology.

View Article >
University of Pennsylvania, Neubauer Family Foundation, and Philadelphia Police Department Partner to Support Police Leadership Education

The first-of-its-kind graduate degree in the U.S. for police leaders launches this fall at the School of Arts & Sciences.

View Article >
Professor of Biology Philip Rea Wins Neal Award for Scientific Journalism

Rea won for the award for Best Technical/Scientific Content for his article “Gliflozins for Diabetes: From Bark to Bench to Bedside,” published in American Scientist.

View Article >
Marisa C. Kozlowski Named Next Associate Dean for the Natural Sciences

Kozlowski, who joined the Penn faculty in 1997, succeeds Mark Trodden, who transitions to the Dean of Penn Arts & Sciences on June 1.

View Article >